Notes from author
This is one of several strategies to beat the last boss, Gwyn.
Equip heavy armor with good physical and fire defense. Using either Iron Flesh or Flash Sweat, two-hand a weapon of your choice and spam him with R1. He staggers easily and his attacks do less damage because of your high defense. If Iron Flesh expires before he is dead, pop a flask and equip a shield. Try to provoke a grab from him and step backwards to recast it.
The Iron Flesh strategy works best for high Vitality and Endurance builds. Iron Flesh expires quickly. Gwyn's attacks decrease Stamina quickly and make it difficult to counter except with Parry/riposte.
Flash Sweat, on the other hand, greatly reduces the fire blast damage when he grabs you (another weakness of the Iron Flesh tank) and lasts longer. In conjunction with the Ring of Steel Protection, Flash Sweat makes HP losses tolerable.
If you have 50 strength Havel's Greatshield has excellent defense and a special L2 that is similar to Iron Flesh. The L2 defense can provide quick cover if Iron Flesh expires.